Rom 8:26-28  "Likewise the Spirit helps us in our weakness. For we do not know what to pray for as we ought, but the Spirit himself intercedes for us with groanings too deep for words. And he who searches hearts knows what is the mind of the Spirit, because the Spirit intercedes for the saints according to the will of God. And we know that for those who love God all things work together for good, for those who are called according to his purpose." 

Loss is the reality of a life focused on the temporal.

Loss of position and prestige, loss of loved ones, loss of possessions, loss of health and vigor. All around us is temporal. 

Yes, and we are weak, though continually trying to hold ourselves out as strong. 

Yet, even this, our weakness and need is turned into goodness toward us by the love given through the Father. He is Absolute Love.

"...as the state of perfection, which consists in the perfect love of God and contempt for self, cannot exist unless it have these two parts, which are the knowledge of God and of oneself, the soul has of necessity to be practised first in the one and then the other, now given to taste of the one-that is, exaltation-and now being made to experience the other-that is, humiliation...

This, as we have said, is an infused and loving knowledge of God, which enlightens the soul and at the same time en-kindles it with love, until it is raised up step by step, even unto God its Creator. For it is love alone that unites and joins the soul with God." 

"Dark Night of the Soul" by St. John of the Cross; cica 1542-1591Translated and Edited by E. Allison Peers, Third Edition Image Books A Division of Doubleday  Garden City, New York 1959

Jas 4:10  "Humble yourselves before the Lord, and he will exalt you."